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Evidence-based clinical practice guidelines for irritable bowel syndrome.
Shin Fukudo1, Hiroshi Kaneko, Hirotada Akiho
1Guidelines Committee for creating and evaluating the "Evidence-based clinical practice guidelines for irritable bowel syndrome", the Japanese Society of Gastroenterology (JSGE), K-18 Building 8F, 8-9-13 Ginza, Chuo, Tokyo, 104-0061, Japan, sfukudo@med.tohoku.ac.jp.
New clinical practice guidelines for irritable bowel syndrome (IBS) were developed in Japan, offering a tailored, stepwise approach to diagnosis and treatment. These evidence-based guidelines consider Japan's unique healthcare system and patient factors.
Area of Science:
- Gastroenterology
- Clinical Practice Guidelines
- Irritable Bowel Syndrome (IBS) Management
Background:
- Irritable bowel syndrome (IBS) care strategies are evolving globally.
- Geographic customization of IBS treatments is crucial due to variations in medical systems, lifestyles, and genetics.
- The Japanese Society of Gastroenterology (JSGE) developed evidence-based clinical practice guidelines for IBS.
Purpose of the Study:
- To establish evidence-based clinical practice guidelines for IBS tailored to the Japanese population.
- To provide a structured approach for the diagnosis and management of IBS.
- To address 62 clinical questions covering IBS definition, epidemiology, pathophysiology, diagnosis, treatment, prognosis, and complications.
Main Methods:
- Development of 62 clinical questions (CQs) based on evidence.
- Formulation of statements to answer each CQ.
- Creation of a diagnostic algorithm incorporating alarm symptoms, risk factors, and routine examinations.
- Establishment of a three-step treatment protocol: diet/behavioral/gut-targeted pharmacotherapy, psychopharmacological agents/psychotherapy, and combined therapies.
Main Results:
- A comprehensive set of guidelines addressing various aspects of IBS.
- A diagnostic algorithm recommending colonoscopy based on specific criteria.
- A three-step therapeutic strategy involving diet, behavioral modification, gut-targeted pharmacotherapy, psychopharmacological agents, and psychotherapy.
- Guidelines are considered well-suited for Japanese IBS patients.
Conclusions:
- The JSGE clinical practice guidelines offer a tailored and stepwise approach to IBS care in Japan.
- These guidelines may offer valuable insights for IBS management in other countries.
- Customization of IBS care is essential to accommodate regional differences in healthcare and patient characteristics.
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