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Updated: Apr 19, 2026

LERLIC-MS/MS for In-depth Characterization and Quantification of Glutamine and Asparagine Deamidation in Shotgun Proteomics
Published on: April 9, 2017
A multi-functional probe to discriminate Lys, Arg, His, Cys, Hcy and GSH from common amino acids
Xiuhong Lu1, Wen Wang, Qian Dong
1School of Pharmacy, Fudan University, Shanghai, 201203, P. R. China. xcdong@fudan.edu.cn zhaoweili@fudan.edu.cn.
Abstract:
The co-existence and similar properties of amino acids make the detection of individual amino acids challenging. Herein we discovered that probe 1 may act as a smart example to classify and differentiate basic amino acids (Arg/Lys/His), thiol-containing amino acids (Cys/HCy), and GSH through different sensing mechanisms in selected environments.
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