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The RIVUR study: a review of its findings

Gabriel Cara-Fuentes1, Nirupama Gupta, Eduardo H Garin

  • 1Division of Pediatric Nephrology, Department of Pediatrics, University of Florida, 1600 SW Archer Rd., HD214, Gainesville, FL, 32610, USA.

Pediatric Nephrology (Berlin, Germany)
|December 16, 2014
PubMed

Insights

Antimicrobial prophylaxis for children with vesicoureteral reflux (VUR) showed a minimal benefit in preventing recurrent urinary tract infections (UTIs) over two years. The study questions current recommendations for UTI management in VUR patients.

Area of Science:

  • Pediatric Nephrology
  • Infectious Diseases
  • Urology

Background:

  • Vesicoureteral reflux (VUR) is a condition that can lead to recurrent urinary tract infections (UTIs) in children.
  • The Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) trial investigated the efficacy of antimicrobial prophylaxis in managing VUR.
  • Previous conclusions suggested prophylaxis reduces UTI risk but not renal scarring.
Abstract

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