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Regional localization of human ecto-5' nucleotidase to chromosome 6q14-q21
J M Boyle1, Y Hey, K H Grzeschik
1Paterson Institute for Cancer Research, Christie Hospital and Holt Radium Institute, Manchester, UK.
Human Genetics
|September 1, 1989
Abstract:
Human and mouse hybrids that contain fragments of human chromosome 6 as translocations were analysed for expression of ecto-5' nucleotidase enzymic activity measured by the conversion of AMP to adenosine and for antigenicity recognized by a monoclonal antibody specific for the human isozyme. Both methods allow a regional assignment of ecto-5'nucleotidase to 6q14-q21.