Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Physiology of Smell and Olfactory Pathway

Physiology of Smell and Olfactory Pathway

Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...

Chemical Signaling in the Endocrine System

Chemical Signaling in the Endocrine System

A signaling cascade is a series of events that facilitates the transmission of information within or between cells, culminating in a targeted response in the recipient cell. As chemical messengers, hormones are pivotal in initiating and modulating these intricate signaling cascades based on their solubility.
Lipid-soluble hormones, such as steroid hormones, demonstrate an intracellular action. These hormones traverse cell membranes due to their lipid nature. Once inside the target cell, they...

Yeast Signaling

Yeast Signaling

Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Retraction: Comparison of the effect of respiratory muscle strength on dynamic and static balance assessment between sarcopenia and non-sarcopenia groups.

Journal of physical therapy science·2026

Same author

Granulosa Cell Tumour in a Spayed Cat With Ovarian Remnant Syndrome and Hyperestrogenaemia Without Estrus Signs.

Veterinary medicine and science·2026

Same author

Development of a transdermal sumatriptan formulation with iontophoresis.

Drug development and industrial pharmacy·2026

Same author

Molecular functions and applications of peptide agonists acting on mouse neuromedin U receptor 1.

Bioorganic & medicinal chemistry·2026

Same author

Improved preparation of Abraxane<sup>®</sup> I.V. Infusion (paclitaxel nanoparticles).

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners·2026

Same author

Catheter-Related Bloodstream Infection in Patients Receiving Vitamin-Enriched Peripheral Parenteral Nutrition: A Retrospective Cohort Study.

Biological & pharmaceutical bulletin·2025

Search research articles

Related Experiment Video

Updated: Apr 19, 2026

Author Spotlight: Examining Volatile Sex Pheromone Influence on Male C. elegans Behavior

Author Spotlight: Examining Volatile Sex Pheromone Influence on Male C. elegans Behavior

Published on: August 9, 2024

Stereochemical studies on pheromonal communications.

¹Photosensitive Materials Research Center, Toyo Gosei Co., Ltd.

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences

|December 16, 2014

Summary

This summary is machine-generated.

Stereochemistry is crucial for pheromone communication. Enantioselective synthesis clarifies how a pheromone

More Related Videos

The Identification of Sea Lamprey Pheromones Using Bioassay-Guided Fractionation

The Identification of Sea Lamprey Pheromones Using Bioassay-Guided Fractionation

Published on: July 17, 2018

In-depth Physiological Analysis of Defined Cell Populations in Acute Tissue Slices of the Mouse Vomeronasal Organ

In-depth Physiological Analysis of Defined Cell Populations in Acute Tissue Slices of the Mouse Vomeronasal Organ

Published on: September 10, 2016

Related Experiment Videos

Last Updated: Apr 19, 2026

Author Spotlight: Examining Volatile Sex Pheromone Influence on Male C. elegans Behavior

Author Spotlight: Examining Volatile Sex Pheromone Influence on Male C. elegans Behavior

Published on: August 9, 2024

The Identification of Sea Lamprey Pheromones Using Bioassay-Guided Fractionation

The Identification of Sea Lamprey Pheromones Using Bioassay-Guided Fractionation

Published on: July 17, 2018

In-depth Physiological Analysis of Defined Cell Populations in Acute Tissue Slices of the Mouse Vomeronasal Organ

In-depth Physiological Analysis of Defined Cell Populations in Acute Tissue Slices of the Mouse Vomeronasal Organ

Published on: September 10, 2016

Area of Science:

Chemical Ecology
Organic Synthesis
Insect Behavior

Background:

Pheromonal communication relies heavily on the precise three-dimensional structure (stereochemistry) of molecules.
Understanding the stereochemistry of pheromones is essential for deciphering insect behavior and developing effective pest control strategies.

Purpose of the Study:

To review the critical role of stereochemistry in pheromone bioactivity.
To highlight how enantioselective synthesis aids in determining the absolute configuration of pheromones.
To illustrate the diverse relationships between pheromone stereochemistry and biological activity.

Main Methods:

Review of existing literature on pheromone synthesis and bioactivity.
Analysis of case studies demonstrating stereochemistry-dependent pheromonal responses.
Discussion of enantioselective synthetic approaches for pheromone characterization.

Main Results:

Pheromone bioactivity is often dictated by specific enantiomers or their ratios.
Enantioselective synthesis provides definitive absolute configurations for naturally occurring pheromones.
The relationship between stereochemistry and bioactivity varies significantly across different pheromone systems, as exemplified by sulcatol.

Conclusions:

Stereochemistry is a key determinant of pheromone efficacy and specificity.
Enantioselective synthesis is a powerful tool for elucidating pheromone structure-activity relationships.
Further research into pheromone stereochemistry can lead to novel applications in chemical ecology and pest management.