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Updated: Apr 19, 2026

Protein Kinase C-delta Inhibitor Peptide Formulation using Gold Nanoparticles
Published on: March 9, 2019
Inhibiting EGFR clustering and cell proliferation with gold nanoparticles
Chiara Paviolo1, James W M Chon, Andrew H A Clayton
1Centre for Micro-Photonics, Faculty of Engineering, Science and Technology, Swinburne University of Technology, Hawthorn, PO Box 218, Victoria, 3122, Australia.
Abstract:
Gold nanoparticles are functionalized with epidermal growth factor (EGF) molecules and incubated with HeLa cells. These new complexes mechanically interfere with the activation of EGF receptors in a length-dependent manner. Protein-functionalized gold nanoparticles hold great potential for unveiling the fundamental characteristics of cell receptors and for future pharmacological studies on receptor targeting.
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