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Updated: Apr 19, 2026

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Compact Quantum Dots for Single-molecule Imaging
Published on: October 9, 2012
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Compact halo-ligand-conjugated quantum dots for multicolored single-molecule imaging of overcrowding GPCR proteins on
Akihito Komatsuzaki1, Tatsuya Ohyanagi, Yoshikazu Tsukasaki
1Laboratory for Nano-Bio Probes, Quantitative Biology Center, Riken, Suita, 565-0874, Osaka, Japan.
Small (Weinheim an Der Bergstrasse, Germany)
|December 16, 2014
Abstract:
To detect single molecules within the optical diffraction limit (< ca. 200 nm), a multicolored imaging technique is developed using Halo-ligand conjugated quantum dots (Halo-QDs; <6 nm in diameter). Using three types of Halo-QDs, multicolored single-molecule fluorescence imaging of GPCR proteins in Dictyostelium cells is achieved.

