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Published on: January 25, 2021
NORMATIVE STANDARDS AND PATTERNING OF FAT AND MUSCLE IN WHITE AND BLACK NEWBORN INFANTS
Jon M Brandt1, G Andrew Allen1, Merlin G Butler1
1Division of Genetics, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Insights
Newborn body composition varies by race and sex. This study provides normative data for fat and muscle measurements in white and black infants, aiding clinical body composition assessment.
Area of Science:
- Pediatric body composition analysis
- Neonatal anthropometry
- Human growth and development
Background:
- Normative data for body composition in newborns is lacking.
- Accurate assessment of newborn body composition is crucial for clinical applications.
- Existing data does not adequately represent diverse racial and ethnic groups.
Purpose of the Study:
- To establish normative data for fat and muscle patterning in white and black newborns.
- To provide standards for sums of fat and muscle areas and muscle circumferences.
- To aid in the clinical assessment of body composition in neonates.
Main Methods:
- Cross-sectional study of white and black newborn infants.
- Measurement of skinfolds, limb fat areas, and muscle circumferences (arm, forearm, thigh, calf).
- Statistical analysis (t-tests) to identify significant differences based on race and sex.
Main Results:
- Significant sex-based differences in fat patterning were observed in white and black newborns.
- Black female newborns had larger fat areas but smaller circumferences than black males.
- White newborns exhibited greater height, medial calf skinfold, and calf fat area compared to black newborns.
Conclusions:
- This study provides essential normative data for newborn body composition, crucial for clinical evaluation.
- Observed differences in fat and muscle patterning highlight the importance of considering race and sex in neonatal assessment.
- The findings can inform clinical practice for assessing growth and nutritional status in newborns.
Abstract:
Due to the lack of normative data in newborns, we report fat and muscle patterning, and standards for the sums of fat and muscle areas and muscle circumferences for arm, forearm, thigh, and calf in white and black newborn infants that may have clinical application in the assessment of body composition in newborns. Significant differences were found between white males and white females in fatness patterning: white female newborns were larger for all 21 variables except height. Statistically significant differences (t test; p < 0.05) existed for five skinfold measurements (forearm, subscapular, suprailiac, thigh, medial calf), three limb fat areas (forearm, thigh, calf), and the sums of the skinfolds and fat areas despite similar limb circumferences. Black female newborns were larger than black males for five of the eight skinfolds (with a significant difference observed in medial calf skinfold), for all of the limb fat areas, and for the sums of the skinfolds and fat areas. Despite their larger skinfolds and fat areas, black females had smaller circumferences. No sex-related trends or significantly different variables were observed in the muscle patterning of white infants. Differences in muscle patterning were observed between black males and black females, with males having larger values for all 14 variables. Statistically significant differences were found between white and black infants, with white newborns having greater height, medial calf skinfold, and calf fat area.
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