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Updated: Apr 19, 2026

In-vitro Reconstitution of Bacterial Ubiquitination and VCP/p97-mediated Elimination
Published on: January 2, 2026
Ubiquitination as an efficient molecular strategy employed in salmonella infection
Lakshmi A Narayanan1, Mariola J Edelmann2
1The Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University , Mississippi State, MS , USA.
Abstract:
The ubiquitin modification has various functions in the host innate immune system in response to the bacterial infection. To counteract the host immunity, Salmonella can specifically target ubiquitin pathways by its effector proteins. In this review, we describe the multiple facets of ubiquitin function during infection with Salmonella enterica Typhimurium and hypothesize how these studies on the host-pathogen interactions can help to understand the general function of the ubiquitination pathway in the host cell.
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