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An Automated MR Image Segmentation System Using Multi-layer Perceptron Neural Network.

S Amiri1, M M Movahedi1, K Kazemi2

  • 1Department of Medical Physics and Biomedical Engineering, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Journal of Biomedical Physics & Engineering
|December 16, 2014
PubMed
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This study presents an automated algorithm using multi-layer perceptron neural networks (MLPNN) for segmenting brain tissues in MR images. The method accurately identifies gray matter (GM) and white matter (WM), aiding in neuro-degenerative disorder research.

Area of Science:

  • Medical Imaging
  • Neuroscience
  • Artificial Intelligence

Background:

  • Accurate brain tissue segmentation in MR images is crucial for analyzing neuro-degenerative disorders and morphological differences.
  • Image artifacts like noise and low contrast can lead to classification errors in segmentation.
  • Volumetric analysis of gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) requires precise segmentation.

Purpose of the Study:

  • To develop an automated algorithm for segmenting human brain 2D structural MR images.
  • To identify and classify white matter (WM) and gray matter (GM) tissues.
  • To utilize multi-layer perceptron neural networks (MLPNN) for improved MR image segmentation.

Main Methods:

  • An automated algorithm based on multi-layer perceptron neural networks (MLPNN) was developed.
Keywords:
Artificial neural networksImage segmentationMulti-layer perceptron

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  • 2D MR images undergo intensity enhancement and removal of non-brain tissue.
  • Each pixel is characterized by 13 features (8 statistical, 5 non-statistical) for classification.
  • Main Results:

    • The algorithm was evaluated on 20 real MR images, demonstrating robust performance.
    • Average Jaccard similarity for GM was 75.7% and for WM was 67.8%.
    • Average Dice similarity for GM was 86.0% and for WM was 80.7%.

    Conclusions:

    • The developed MLPNN-based method shows promising results for 2D MR image segmentation.
    • The algorithm effectively categorizes white matter (WM) and gray matter (GM).
    • This method can assist in the segmentation of MR images, particularly for WM and GM analysis.