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The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
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Chronic meningitis in systemic lupus erythematosus: An unusual etiology

Anu Gupta1, Vishal Jogi1, Manoj Kumar Goyal1

  • 1Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Annals of Indian Academy of Neurology
|December 16, 2014
PubMed

Insights

Systemic lupus erythematosus (SLE) can rarely cause chronic aseptic meningitis. A thorough cerebrospinal fluid (CSF) analysis is crucial for accurate diagnosis and to prevent mortality in SLE patients.

Area of Science:

  • Neurology
  • Rheumatology
  • Infectious Diseases

Background:

  • Chronic aseptic meningitis is an uncommon neurological manifestation of Systemic Lupus Erythematosus (SLE).
  • Differential diagnosis includes immunological factors, drug toxicity, and unidentified viral infections.
  • Prompt and thorough cerebrospinal fluid (CSF) analysis is critical in SLE patients presenting with meningitis symptoms.

Observation:

  • A case report of a young female SLE patient with chronic meningitis of an unusual cause is presented.
  • The patient's presentation mimicked meningitis, necessitating comprehensive etiological investigation.
  • The etiology was ultimately identified as an uncommon cause, distinct from typical SLE disease activity or drug side effects.

Findings:

  • The presented case highlights a rare etiology of aseptic meningitis in SLE.
  • Complete CSF workup was essential to rule out common causes and identify the specific etiology.
  • The findings underscore the importance of detailed diagnostic procedures in complex SLE cases.

Implications:

  • Accurate diagnosis of meningitis in SLE is vital to guide appropriate treatment and improve patient outcomes.
  • This case broadens the understanding of potential neurological complications in SLE.
  • Emphasizes the need for a high index of suspicion for diverse etiologies of meningitis in SLE patients.
Keywords:
HSV-2Herpes simplex viruslupusmeningitissystemic lupus erythematosus

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