Rowell syndrome.

Area of Science:

• Dermatology
• Rheumatology
• Rare Diseases

Background:

• Rowell syndrome is a rare autoimmune disorder characterized by erythema multiforme-like skin lesions and systemic lupus erythematosus.
• The condition predominantly affects middle-aged women, with limited pediatric case reports.

Observation:

• This report details a rare presentation of Rowell syndrome in a 15-year-old male patient.
• The patient exhibited characteristic erythema multiforme-like lesions and lupus erythematosus.
• The diagnosis was confirmed through clinical and laboratory findings consistent with Rowell syndrome.

Findings:

• The adolescent patient demonstrated a significant positive response to treatment with systemic corticosteroids.
• Hydroxychloroquine therapy was also initiated and found to be effective in managing the condition.
• The treatment regimen led to the resolution of skin lesions and control of systemic lupus erythematosus manifestations.

Implications:

• This case expands the known demographic profile of Rowell syndrome, indicating it can occur in adolescent males.
• The successful use of systemic steroids and hydroxychloroquine suggests these as viable therapeutic options for pediatric cases.
• Further research into pediatric Rowell syndrome is warranted to understand its specific clinical course and optimal management strategies.