Related Experiment Video
Updated: Apr 19, 2026

Generation of Fluorescent Protein Fusions in Candida Species
Published on: March 4, 2017
Congenital candidiasis
Chintaginjala Aruna1, Kolalapudi Seetharam1
1Department of Dermatology, Venereology and Leprosy, Katuri Medical College, Guntur, Andhra Pradesh, India.
Abstract:
Congenital candidiasis (CC) is a rare disease with less than 100 cases being reported in the literature. It presents within six days of life with manifestations ranging from localized skin disease to systemic involvement in the form of respiratory distress, sepsis, and death. We report a neonate who presented with diffuse pustular eruption on erythematous background involving face, trunk, and palms within 24 h after birth. Candida albicans was identified in 10% potassium hydroxide (KOH) smear and culture from the pustules. Intravenous fluconazole and topical ketoconazole were given and the condition improved completely in two weeks. CC is rare and needs to be differentiated from other conditions presenting with pustular lesions at birth in order to avoid complications. Early diagnosis and prompt treatment of this condition is important as untreated cases carry a mortality rate of 8-40%.
Related Concept Videos
Cytomegalovirus Disease
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Sexually Transmitted Infections
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
Development of the Oral Microbiota

