Related Experiment Video
Updated: Apr 19, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
Published on: March 23, 2014
Prevalence of restless legs syndrome among leprosy patients: a hospital based study
Introduction And Objectives:
Restless legs syndrome (RLS) is a type of neurological disorder which presents with an uncontrollable urge to move legs and arms. It commonly affects legs more than arms. Data regarding prevalence of restless legs syndrome in leprosy are sparse. The aims and objectives of the study were to find out the prevalence of RLS in people affected by leprosy and to determine the presence and magnitude of sleep disruption in leprosy patients with RLS.
Materials And Methods:
Total 143 patients diagnosed with leprosy were enrolled in the study. A diagnosis of RLS and a severity assessment were made using the criteria described by International Restless Legs Syndrome Study Group. The Pittsburgh Sleep Quality Index (PSQI) was evaluated in all those who were diagnosed with RLS.
Results:
Out of 143 patients recruited in the study, 56 (39.16%) patients were found to be suffering from RLS. Mean Pittsburgh Sleep Quality Index global score was higher (16.55), and the value was specifically higher among patients presenting with Type-2 lepra reaction (17.8) and pure neuritic leprosy (15.93).
Conclusions:
The frequency of RLS among leprosy patients is significantly higher. They suffer from bad sleep quality at night which significantly affects their quality of life. So all patients affected with leprosy should be evaluated for RLS and early treatment should be started to improve their sleep.
More Related Videos
11:36Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
Published on: April 21, 2012
12:49Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation
Published on: March 21, 2020
Related Concept Videos
Restless Leg Syndrome and Night Terrors
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
REM Sleep Behavior Disorder
RBD is significantly associated with...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation