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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Related Experiment Video

Updated: Apr 19, 2026

Plaquing of Herpes Simplex Viruses
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[Herpes gestationis. A case report].

Jorge Arturo Moreno-Diaz, Vanessa Paredes-Solis, Blanca de Jesús Martínez-Chagolla

    Ginecologia Y Obstetricia De Mexico
    |December 17, 2014
    PubMed
    Summary
    This summary is machine-generated.

    A pregnant woman with a severe skin condition was diagnosed with gestational herpes and secondary bacterial infection, not Kaposi sarcoma or HIV. Prompt diagnosis and treatment are crucial for maternal and fetal health.

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    Area of Science:

    • Dermatology
    • Infectious Diseases
    • Obstetrics

    Background:

    • A 30-week pregnant patient presented with a complex, three-month history of a severe, multi-treated skin condition.
    • Initial differential diagnoses included Kaposi sarcoma and suspected Human Immunodeficiency Virus (HIV) infection.

    Observation:

    • The patient exhibited widespread, painful, and itchy exulcerations with purulent discharge, leading to dysphagia.
    • Laboratory findings revealed normochromic normocytic anemia, elevated inflammatory markers (ESR, PCR), hypocalcemia, and positive IgG for TORCH infections.

    Findings:

    • Histopathological analysis and direct immunofluorescence confirmed herpes virus infection.
    • Bacterial cultures identified coagulase-negative Staphylococcus and Enterobacter cloacae, indicating a secondary pyogenic infection.

    Implications:

    • The case highlights the importance of considering gestational herpes in pregnant patients with severe dermatological manifestations.
    • Accurate diagnosis, differentiating from other conditions like Kaposi sarcoma and HIV, is critical for appropriate management.
    • Management involved addressing both the viral herpes infection and secondary bacterial superinfections.