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What is your patient's cognitive profile? Three distinct subgroups of cognitive function in persons with heart
Misty A W Hawkins1, Julie T Schaefer1, John Gunstad1
1Department of Psychology, Kent State University, Kent, OH.
Purpose:
The aim of this study was to determine whether patients with heart failure (HF) have distinct profiles of cognitive impairment.
Background:
Cognitive impairment is common in HF. Recent work found three cognitive profiles in HF patients-(1) intact, (2) impaired, and (3) memory-impaired. We examined the reproducibility of these profiles and clarified mechanisms.
Methods:
HF patients (68.6 ± 9.7 years; N=329) completed neuropsychological testing. Composite scores were created for cognitive domains and used to identify clusters via agglomerative-hierarchical cluster analysis.
Results:
A 3-cluster solution emerged. Cluster 1 (n=109) had intact cognition. Cluster 2 (n=123) was impaired across all domains. Cluster 3 (n=97) had impaired memory only. Clusters differed in age, race, education, SES, IQ, BMI, and diabetes (ps ≤ .026) but not in mood, anxiety, cardiovascular, or pulmonary disease (ps ≥ .118).
Conclusions:
We replicated three distinct patterns of cognitive function in persons with HF. These profiles may help providers offer tailored care to patients with different cognitive and clinical needs.
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