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Updated: Apr 19, 2026
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Evaluation of Nanoparticle Uptake in Tumors in Real Time Using Intravital Imaging
Published on: June 21, 2011
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Targeted labeling of an early-stage tumor spheroid in a chorioallantoic membrane model with upconversion
Kai Liu1, Jasmin A Holz, Yadan Ding
1State Key Laboratory of Luminescence and Application, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Science, Changchun 130033, P. R. China. xgkong14@ciomp.ac.cn.
Nanoscale
|December 17, 2014
Abstract:
In vivo detection of cancer at an early-stage, i.e. smaller than 2 mm, is a challenge in biomedicine. In this work target labeling of an early-stage tumor spheroid (∼500 μm) is realized for the first time in a chick embryo chorioallantoic membrane (CAM) model with monoclonal antibody functionalized upconversion nanoparticles (UCNPs-mAb).
