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Renal transplantation in 2014: renal transplantation-reducing risk and improving outcome

Dennis A Hesselink1, Willem Weimar1

  • 1Erasmus MC, University Medical Centre Rotterdam, Department of Internal Medicine, Division of Nephrology and Renal Transplantation, Room D-427, P.O. Box 2040, Rotterdam, 3000 CA, Netherlands.

Nature Reviews. Nephrology
|December 17, 2014
PubMed

Insights

Recent research offers insights into kidney transplant care. Key findings address living donor risks, alemtuzumab induction therapy effectiveness, and managing chronic hepatitis E virus infection for better patient outcomes.

Area of Science:

  • Nephrology
  • Transplantation Immunology
  • Infectious Diseases

Background:

  • Renal transplantation is a critical treatment for end-stage renal disease.
  • Optimizing long-term care for transplant recipients remains a priority.
  • Advances in 2014 provided new data on key aspects of kidney transplant management.

Purpose of the Study:

  • To review recent (2014) studies relevant to renal transplant recipients.
  • To highlight advancements in understanding donor risks, induction therapy, and viral infections.

Main Methods:

  • Literature review of selected 2014 publications.
  • Analysis of studies focusing on living kidney donation risks.
  • Evaluation of alemtuzumab induction therapy efficacy and safety data.
  • Review of chronic hepatitis E virus infection treatment strategies.

Main Results:

  • Identified potential risks associated with living kidney donation.
  • Assessed the efficacy and safety profile of alemtuzumab-based induction therapy.
  • Examined current approaches for treating chronic hepatitis E virus infection in transplant patients.

Conclusions:

  • The reviewed 2014 studies offer valuable information for enhancing renal transplant recipient care.
  • Understanding donor risks, optimizing induction protocols, and managing infections are crucial for long-term success.

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