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Related Experiment Videos

[Optic neuritis in childhood (author's transl)].

P Haller, U Patzold

    Fortschritte Der Neurologie, Psychiatrie, Und Ihrer Grenzgebiete
    |April 1, 1979
    PubMed
    Summary

    Pediatric optic neuritis, often bilateral with papilledema, can cause persistent visual deficits. Early signs may not include typical central scotoma, and half of affected children later show multiple sclerosis symptoms.

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    SPECT study of a German CADASIL family: a phenotype with migraine and progressive dementia only.

    Neurology·1998

    Area of Science:

    • Ophthalmology
    • Neurology
    • Pediatrics

    Context:

    • Optic neuritis in children presents unique diagnostic and prognostic challenges.
    • Understanding the acute and long-term visual consequences is crucial for pediatric care.

    Purpose:

    • To describe the clinical presentation and visual outcomes of optic neuritis in children.
    • To assess the long-term neurological sequelae, specifically multiple sclerosis development.

    Summary:

    • Twenty-one children under 15 with optic neuritis were studied.
    • Presentations included bilateral optic neuritis and papilledema; central scotomas were not universal in the acute phase.
    • Persistent visual impairment (reduced visual acuity and visual field defects) was common, with half developing multiple sclerosis signs within years.

    Impact:

    • Highlights the potential for lasting visual impairment following pediatric optic neuritis.
    • Underscores the significant risk of developing multiple sclerosis in children with optic neuritis.
    • Informs clinical expectations and follow-up strategies for affected children and their families.

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