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Updated: Apr 19, 2026
Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues
Published on: April 26, 2024
Effect of remineralizing agents on surface microhardness of primary and permanent teeth after erosion
Nikita Agrawal1, N D Shashikiran, Shilipi Singla
1Department of Pedodontics and Preventive Dentistry, People's College of Dental Science and Research Centre, Bhopal, Madhya Pradesh, India.
Purpose:
The purposes of this study were to compare the susceptibility of human primary and permanent enamel to dental erosion caused by soft drinks and to compare in vitro the remineralization potential of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) paste, 1.23 percent acidulated phosphate fluoride (APF) gel, and iron supplement.
Methods:
Fifteen extracted primary and permanent teeth were used for sample preparation. Samples were randomly divided into three treatment groups: CPP-ACP paste, APF gel and iron supplement. The samples were subjected to a series of demineralization and remineralization cycles and were evaluated through surface microhardness. Statistical analysis was performed using one way ANOVA and unpaired t -tests.
Results:
After remineralization, all samples showed an increase in surface hardness, which was significantly higher with CPP-ACP paste.
Conclusion:
CPP-ACP paste was more effective at preventing dental erosion than the other products.
