Related Experiment Video
Updated: Apr 19, 2026

Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy
Published on: October 24, 2025
[Perioperative antibiotic prophylaxis during standard interventions in ear, nose and throat medicine]
U Walliczek1, C Thorn, M Königstein
1Universitäts-HNO-Klinik Mannheim, Mannheim, Deutschland, wallicze@staff.uni-marburg.de.
Background:
The majority of standard interventions in otorhinolaryngology are classified as "clean contaminated" according to international classifications; correspondingly, no generally accepted recommendations regarding perioperative antibiotic prophylaxis (pAP) exist. The value of such pAP for these interventions remains unclear. Aim of the study was to assess the effects of pAP in selected standard otorhinolaryngologic procedures.
Materials And Methods:
In August 2012 a standard operating procedure (SOP) was implemented, which lead to termination of routine pAP for the majority of standard operations. All patients included in this retrospective study had undergone a standard procedure (tonsil, septum or paranasal sinus surgery) during a period either 6 months before or 6 months after the inauguration of the SOP. The charts were reviewed for demographic factors, postoperative complications and length of hospital stay.
Results:
The group before the inauguration of the SOP consisted of 316 patients (132 female, 184 male), aged 30±20 years. The group after the inauguration comprised 308 patients (128 female, 180 male), aged 31±19 years. For the entire patient collective, the termination of pAP led to a statistically significant increase in postoperative antibiotic treatment for all types of interventions tested. A statistically significant change in noninflammatory complications or the length of hospital stay was not detected.
Discussion:
The termination of pAP during standard procedures in otorhinolaryngology is associated with an increase in postoperative antibiotic treatment but has no effect on other postoperative complications tested or the length of hospital stay.
Insights
Stopping routine perioperative antibiotic prophylaxis (pAP) for standard ear, nose, and throat surgeries increased postoperative antibiotic use. However, this change did not affect other complications or hospital stay duration.
Area of Science:
- Otorhinolaryngology
- Surgical Infection Prevention
- Clinical Practice Guidelines
Context:
- Standard otorhinolaryngologic procedures are often classified as 'clean contaminated'.
- Existing guidelines for perioperative antibiotic prophylaxis (pAP) in these procedures are lacking.
- The clinical value of pAP for such interventions remains uncertain.
Purpose:
- To evaluate the impact of discontinuing routine perioperative antibiotic prophylaxis (pAP) in standard otorhinolaryngologic surgeries.
- To assess changes in postoperative complications and hospital stay after implementing a new standard operating procedure (SOP) that terminated routine pAP.
- To analyze the effects of altering pAP protocols on patient outcomes in ear, nose, and throat procedures.
Summary:
- A retrospective study compared outcomes before and after implementing an SOP that ceased routine pAP for tonsil, septum, and paranasal sinus surgeries.
- The study included 316 patients pre-SOP and 308 patients post-SOP.
- Termination of pAP resulted in a statistically significant increase in postoperative antibiotic treatment across all tested interventions.
Impact:
- Discontinuation of pAP in standard otorhinolaryngologic procedures leads to increased postoperative antibiotic treatment.
- There was no statistically significant change in non-inflammatory complications or length of hospital stay following the termination of pAP.
- Findings suggest a need to re-evaluate antibiotic prophylaxis protocols in clean contaminated surgical procedures.
More Related Videos
Related Concept Videos
Epistaxis
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Tonsillitis II: Management
Suctioning the Nasopharyngeal Airway
Equipment Required
Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Tracheostomy Care I: Pre-procedural Steps
Required Equipment
The equipment necessary for tracheostomy care includes:

