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Isolation and Analysis of Hematopoietic Stem Cells from the Placenta
Published on: June 24, 2008
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Early post-partum hematological changes in Holstein dairy cows with retained placenta
Pierangelo Moretti1, Monica Probo2, Nicola Morandi3
1Department of Veterinary Science and Public Health, University of Milan, via Celoria 10, 20133 Milan, Italy; Central Laboratory, Veterinary Teaching Hospital, University of Milan, via dell'Università 6, 26900 Lodi, Italy.
Animal Reproduction Science
|December 18, 2014
Summary
Retained placenta in dairy cows is linked to specific blood changes. Neutropenia (low neutrophil count) may contribute to retained placenta development, but further research is needed.
Area of Science:
- Veterinary Medicine
- Animal Science
- Reproductive Biology
Background:
- Retained placenta (RP) is a common postpartum complication in dairy cattle.
- The role of hematological changes and acute phase reactions in RP pathogenesis is not well understood.
Purpose of the Study:
- To investigate hematological alterations in dairy cows with RP in the early postpartum period.
- To determine if these hematological changes are associated with an acute phase reaction.
Main Methods:
- Retrospective analysis of hematology, acute phase proteins, inflammation markers, and serum biochemistry data from 45 dairy cows (22 RP, 23 controls).
- Data collected at 3±1 days in milk from the ProZoo project database.
- Statistical comparison between RP and control groups.
Main Results:
- Cows with RP showed significantly higher RBC count, d-ROMs concentration, and AST activity compared to controls.
- Neutrophils, thiol groups, and serum zinc concentration were significantly lower in the RP group.
- These findings suggest a potential link between specific hematological changes and RP.
Conclusions:
- Retained placenta is a multifactorial syndrome.
- Neutropenia may be a contributing factor in RP pathogenesis.
- Further studies are required to elucidate the precise role of neutropenia in RP development and its relationship to inflammatory changes.
