Hyaluronidase in ophthalmic evisceration surgery

Area of Science:

• Ophthalmology
• Surgical Innovation

Background:

• Evisceration surgery aims to remove intraocular contents.
• Conventional methods can be time-consuming and challenging.

Purpose of the Study:

• To evaluate the effectiveness of hyaluronidase in ophthalmic evisceration surgery.
• To compare hyaluronidase-assisted removal with conventional and isotonic fluid methods.

Main Methods:

• A comparative study involving 34 patients across three groups: conventional surgery, isotonic fluid, and hyaluronidase.
• Hyaluronidase or isotonic fluid was introduced into the uveo-scleral space.
• Intraocular content removal was attempted using a one-scoop method.

Main Results:

• Complete one-scoop removal was achieved in 77% of the hyaluronidase group versus 50% in the isotonic fluid group.
• Fluid introduction was necessary for all successful one-scoop removals.
• Procedure durations were significantly shorter in the hyaluronidase group (P < 0.05).

Conclusions:

• Hyaluronidase significantly facilitates and accelerates the removal of intraocular content during ophthalmic evisceration.
• This enzymatic approach enhances surgical efficiency and completeness.