Related Experiment Video
Updated: Apr 19, 2026

Left Coronary Artery Ligation: A Surgical Murine Model of Myocardial Infarction
Published on: August 9, 2022
Role of toll-like receptors in myocardial infarction
Yu Sun1, Wen-Zhou Liu1, Tao Liu1
1a Department of Cardio-Thoracic Surgery , The First Affiliated Hospital of GuangXi Medical University , NanNing , China.
Abstract:
Toll-like receptors (TLRs) play a pivotal role in both innate and adaptive immunity, and TLRs recognize invading pathogens through molecular pattern recognition, and ultimately lead to the activation of transcription factors and inflammatory responses. Myocardial infarction leads to changes in the remodeling of the left ventricle of the heart, and the degree and type of remodeling provides important diagnostic information for the therapeutic management of ischemic heart disease. Innate immune takes a most important role in myocardial infarction. There are some studies reporting that TLRs play an important role in the myocardial infarction. The literatures were searched extensively and this review was performed to review the role of TLRs in myocardial infarction.
Related Concept Videos
Myocarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis III: Medical Management
Coronary Artery Disease II: Pathophysiology
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome IV: Interprofessional Care

