Related Experiment Video
Updated: Apr 19, 2026

09:57
18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography
Published on: January 11, 2020
8.2K
Synthesis and evaluation of a boronate-tagged 1,8-naphthalimide probe for fluoride recognition
Su-Ying Xu1, Xiaolong Sun, Haobo Ge
1Department of Chemistry, University of Bath, Bath BA2 7AY, UK. t.d.james@bath.ac.uk s.pascu@bath.ac.uk.
Organic & Biomolecular Chemistry
|December 18, 2014
Abstract:
A biocompatible fluoride receptor has been developed where the interaction between the boronic acid ester and amine (NH) results in fluoride ion selectivity and enhanced fluorescence quenching.
Related Concept Videos
Labeling DNA Probes
9.9K
DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
9.9K
Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene
8.2K
Bromination and chlorination of aromatic rings by electrophilic aromatic substitution reactions are easily achieved, but fluorination and iodination are difficult to achieve. Fluorine is so reactive that its reaction with benzene is difficult to control, resulting in poor yields of monofluoroaromatic products. To address this, Selectfluor reagent is used as a fluorine source in which a fluorine atom is bonded to a positively charged nitrogen.
8.2K

