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Voltage-dependent transient calcium currents in freshly dissociated capillary endothelial cells
J L Bossu1, A Feltz, J L Rodeau
1Laboratoire d'Etude des Régulations Physiologiques, Centre National de la Recherche Scientifique, Strasbourg, France.
FEBS Letters
|September 25, 1989
Abstract:
Dissociated capillary endothelial cells display a voltage-dependent Ca current activating around the resting potential. The initial transient component of the current corresponds to a Ca channel of the T type. Some cells also display a plateau component corresponding to a distinct dihydropyridine-sensitive Ca channel. Depolarization induced by high external K+ elicits an increase in cytoplasmic Ca concentration. Confluent cells have been found to express the same Ca permeabilities.