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Exposure to extremely low-frequency magnetic field affects biofilm formation by cystic fibrosis pathogens
Giovanni Di Bonaventura1, Arianna Pompilio, Valentina Crocetta
1Department of Experimental & Clinical Sciences, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.
Aims:
To evaluate the in vitro effects of extremely low-frequency magnetic field (ELF-MF) on growth and biofilm formation by Staphylococcus aureus, Pseudomonas aeruginosa, Burkholderia cepacia and Stenotrophomonas maltophilia strains from cystic fibrosis patients.
Materials & Methods:
The motion of selected ions (Fe, Ca, Cu, Zn, Mg, K, Na) was stimulated by the ion resonance effect, then influence on growth and biofilm formation/viability was assessed by spectrophotometry or viability count.
Results:
Generally, exposure to ELF-MF significantly increased bacterial growth and affected both biofilm formation and viability, although with differences with regard to ions and species considered.
Conclusion:
Exposure to ELF-MF represents a possible new approach for treatment of biofilm-associated cystic fibrosis lung infections.
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