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Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

4
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
4

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Related Experiment Video

Updated: Apr 19, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

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Published on: June 30, 2014

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[Neuropsychological tests in multiple sclerosis].

Akitoshi Takeda

    Nihon Rinsho. Japanese Journal of Clinical Medicine
    |December 19, 2014
    PubMed
    Summary
    This summary is machine-generated.

    Cognitive impairment affects 40-65% of multiple sclerosis (MS) patients, impacting social and work life even in early disease stages. Neuropsychological tests are crucial for assessing cognitive decline and treatment outcomes in MS.

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    Area of Science:

    • Neurology
    • Neuropsychology

    Context:

    • Multiple sclerosis (MS) is a chronic neurological disease.
    • Cognitive impairment is a common and early symptom in MS, affecting 40-65% of patients.
    • Cognitive decline impacts social functioning and employment.

    Purpose:

    • To highlight the prevalence and early onset of cognitive impairment in MS.
    • To identify key cognitive domains affected in MS.
    • To emphasize the role of neuropsychological assessments in MS management.

    Summary:

    • Cognitive impairment is prevalent in multiple sclerosis (MS), occurring even in early stages like clinically isolated syndrome.
    • Key affected cognitive domains include processing speed, memory, word retrieval, visuospatial processing, and executive function.
    • Standardized tests like the Brief Repeatable Battery of Neuropsychological Tests (BRB-N) and Minimal Assessment of Cognitive Function in MS (MACFIMS) are used for evaluation.

    Impact:

    • Neuropsychological assessments are vital for predicting prognosis in MS patients.
    • These assessments aid in evaluating the effectiveness of treatments in clinical trials.
    • Understanding cognitive impact is essential for patient support and management strategies.