[Neuropsychological tests in multiple sclerosis]

The prevalence of cognitive impairment is about 40-65% in patients with multiple sclerosis (MS). Cognitive decline appears in MS in the early stages of the disease including clinically isolated syndrome and radiologically isolated syndrome. Cognitive impairments in patients with MS influence their social functioning and employment. Various domains of cognitive function, including processing speed/working memory, long-term memory, word retrieval, visuospatial processing, and executive function are affected in patients with MS. The Brief Repeatable Battery of Neuropsychological Tests (BRB-N) in MS and the Minimal Assessment of Cognitive Function in MS (MACFIMS) are commonly utilized to assess cognitive function in patients with MS. Neuropsychological assessments are important in MS to predict prognosis and cognitive outcome in treatment trials.