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Updated: Apr 19, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Insights
Kawasaki disease (KD) coronary artery lesion (CAL) monitoring can be done noninvasively. Magnetic resonance coronary angiography (MRCA) and multi-detector row computed tomography (MDCT) reduce the need for conventional coronary angiography (CAG).
Area of Science:
- Cardiology
- Pediatric Cardiology
- Diagnostic Imaging
Background:
- Coronary arterial lesions (CAL) resulting from Kawasaki disease (KD) necessitate lifelong monitoring, traditionally via conventional coronary angiography (CAG).
- Advancements in noninvasive imaging modalities, specifically multi-detector row computed tomography (MDCT) and magnetic resonance coronary angiography (MRCA), offer promising alternatives.
Purpose of the Study:
- To evaluate the utility of MRCA and MDCT in monitoring coronary arterial lesions (CAL) in patients with Kawasaki disease (KD).
- To assess the potential of these noninvasive techniques to reduce the frequency of invasive conventional coronary angiography (CAG).
Main Methods:
- Retrospective analysis of 1,200 Kawasaki disease (KD) patients who underwent magnetic resonance coronary angiography (MRCA) since 1999.
- Simultaneous MR myocardial imaging was performed in patients with severe stenotic lesions.
- Multi-detector row computed tomography (MDCT) was utilized for screening and diagnosis in adults presenting with chest pain.
Main Results:
- Magnetic resonance coronary angiography (MRCA) proved effective for monitoring coronary arterial lesions (CAL) in pediatric populations.
- Multi-detector row computed tomography (MDCT) demonstrated efficiency in screening for CAL and ruling out acute coronary syndromes in adults.
- Both noninvasive modalities showed significant potential in minimizing the need for conventional coronary angiography (CAG).
Conclusions:
- Noninvasive magnetic resonance coronary angiography (MRCA) is a valuable tool for monitoring coronary arterial lesions (CAL) in children with Kawasaki disease (KD).
- Multi-detector row computed tomography (MDCT) is an efficient method for screening coronary arterial lesions (CAL) and diagnosing acute coronary syndromes in adults.
- These advanced imaging techniques can significantly reduce the number of invasive conventional coronary angiography (CAG) procedures required.
Abstract:
Coronary arterial lesions (CAL) due to Kawasaki disease (KD) should be monitored by conventional coronary angiography(CAG) throughout their lives. However, recently multi detector row computed tomography(MDCT) and magnetic resonance coronary angiography (MRCA) have developed remarkably. We performed MRCA in 1,200 cases of KD (age at 4 month to 41 years: medium 8 years) since 1999. MR myocardial imaging is also performed simultaneously in patients with severe stenotic lesions. Noninvasive MRCA is useful to monitor CAL in young children. MDCT is efficient at screening of CAL and at making a diagnosis of no acute coronary syndromes in adults with chest pain. These examinations are very useful to decrease CAG to the least times as possible.
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