Related Experiment Video
Updated: Apr 19, 2026

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
Published on: May 8, 2018
[Selective internal radiotherapy (SIRT) of liver tumors]
1Klinische Abteilung für Nuklearmedizin, Universitätsklinik für Radiologie und Nuklearmedizin, Medizinische Universität Wien, Wien, Österreich.
Methodical Innovations:
Selective internal radiotherapy (SIRT) is a safe and efficacious, minimally invasive procedure to treat primary and secondary unresectable liver tumors. For hepatocellular carcinoma (HCC), SIRT has proven to be a well-tolerated therapy option even in advanced stages of disease.
Standard Radiological Methods:
In cases of portal vein thrombosis SIRT is the alternative to transarterial chemoembolization (TACE).
Performance:
The role of SIRT regarding downstaging and bridging to transplantation is promising and SIRT has also been shown to be highly effective and well-tolerated in metastastic liver disease.
Achievements:
The results of prospective randomized trials are awaited to prove the efficiency and safety of SIRT described in numerous retrospective and prospective non-randomized studies.
Practical Recommendations:
The indications are established within the framework of a tumor board.

