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A Porcine Model of Acute Autologous Pulmonary Embolism
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Deceased elderly in-patients with pulmonary embolism
Bratislavske Lekarske Listy
|December 19, 2014
Summary
Pulmonary embolism (PE) is a significant threat in the elderly, often presenting with non-specific symptoms. This study highlights the critical importance of recognizing PE, especially its silent forms, to reduce mortality in older populations.
Area of Science:
- Gerontology
- Cardiology
- Public Health
Background:
- Pulmonary embolism (PE) poses a significant mortality risk in the elderly.
- Clinical signs of PE in older adults are often non-specific, leading to potential underestimation or overestimation.
Purpose of the Study:
- To analyze the influence of age, gender, and immobility on the occurrence of PE and sudden death in elderly patients.
- To compare these factors in a retrospective, long-term study.
Main Methods:
- Retrospective analysis of 12,746 elderly patients (65+ years) hospitalized between 1995 and 2012.
- Inclusion of patient records, death documentation, and autopsy findings for PE-related deaths.
- Analysis of demographic data including age, gender, and immobility status.
Main Results:
- PE was diagnosed in 5.5% (700/12,746) of hospitalized elderly patients.
- The study involved a high proportion of women (66.3%) and men (33.7%).
- Among diagnosed PE cases, 60.6% (424/700) of patients survived.
Conclusions:
- The high incidence of PE, particularly silent forms, significantly contributes to mortality in the elderly.
- Recommendations emphasize avoiding underestimation of PE and implementing preventive measures across all elderly age groups, including the frail.
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