Related Experiment Video
Updated: Apr 19, 2026

In Vivo Electrophysiological Measurements on Mouse Sciatic Nerves
Published on: April 13, 2014
[Young adults' lower limb neuroconduction study reference values]
Sandra M Barrera-Castro1, Fernando Ortiz-Corredor2
1Departamento de Medicina Física y Rehabilitación, Universidad Nacional de Colombia, Bogotá, Colombia.
Objective:
Establishing reference values for neuroconduction studies regarding the peroneal, tibial and sural nerves in a group of young adults.
Materials And Methods:
Neuroconduction was tested (also known as nerve conduction velocity (NCV) tests) on 155 asymptomatic subjects' tibial, peroneal and sural nerves using current conventional techniques, after informed written consent had been obtained. Reference values were obtained and presented as averages, standard deviations and percentiles, along with their correlation with parameters such as age, weight and height, via bivariate analysis of linear correlation using Spearman's rank correlation test.
Results:
Peroneal nerve average distal latency was 3.6 ms (0.4 SD), amplitude 6.1 mV (2.0 SD) and conduction velocity 54.8m/s (4.2 SD). Average tibial nerve distal latency was 3.5 ms (0.4 SD), amplitude 16.7mV (4.7 SD) and conduction velocity 53 m/s (3.8 SD). Average sural nerve peak latency was 3.4 ms (0.3 SD) and amplitude 21.3V (5.0 SD). Peroneal and tibial nerve upper limit of normal side to side variation was 0.8ms (average+2DE) and 0.4 ms (average + 2 SD) for the sural nerve. A statistically significant relationship was found with variables such as weight, height and age.
Conclusions:
The values so obtained could be used in Colombia's electrophysiology laboratories as reference in evaluating patients' suffering musculoskeletal pathologies and different types of polyneuropathy.
Related Concept Videos
Propagation Speed of Electromagnetic Waves
Action Potential
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Local Anesthetics: Differential Sensitivity of Nerve Fibers
Electrophysiology of Normal Cardiac Rhythm

