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Malignant hyperthermia in a trauma patient
Valerie Carpenter1, Brenton LaRiccia, Peter J Papadakos
1Valerie Carpenter is a student in the PA program at Daemen College in Amherst, N.Y. Brenton LaRiccia is lead PA in the Kessler Family Burn/Trauma ICU at the University of Rochester (N.Y.) Medical Center. Peter J. Papadakos is director of critical care medicine and a professor of anesthesiology, surgery, neurosurgery, and neurology at the University of Rochester Medical Center. The authors have disclosed no potential conflicts of interest, financial or otherwise.
Malignant hyperthermia is a severe reaction to anesthesia. Early screening and prompt management are vital for patient safety during and after surgery.
Area of Science:
- Anesthesiology
- Pharmacology
- Medical Genetics
Background:
- Malignant hyperthermia (MH) is a rare but life-threatening pharmacogenetic disorder.
- Exposure to volatile anesthetics and succinylcholine can trigger MH episodes.
- MH is characterized by hypermetabolism, muscle rigidity, and rapid temperature increase.
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