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Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

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Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
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Related Experiment Video

Updated: Apr 19, 2026

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience
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Risk factors for complications after laparoscopic major hepatectomy.

T Nomi1, D Fuks, M Govindasamy

  • 1Department of Digestive Disease, Institut Mutualiste Montsouris, Université Paris Descartes, Paris, France; Department of Surgery, Nara Medical University, Nara, Japan.

The British Journal of Surgery
|December 19, 2014
PubMed
Summary

Purely laparoscopic major hepatectomy (MH) is safe, but surgeons should avoid simultaneous radiofrequency ablation (RFA) and bilobar resection to reduce complications. This study identifies key risk factors for adverse outcomes in laparoscopic MH.

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Area of Science:

  • Hepatobiliary Surgery
  • Minimally Invasive Surgery
  • Surgical Oncology

Background:

  • Laparoscopic major hepatectomy (MH) is increasingly adopted in specialized centers.
  • Limited data exists on the outcomes and risk factors associated with purely laparoscopic MH.
  • This study aims to identify risk factors for postoperative complications in purely laparoscopic MH.

Purpose of the Study:

  • To identify risk factors for overall and major postoperative complications after purely laparoscopic major hepatectomy.
  • To evaluate the safety and feasibility of purely laparoscopic MH.
  • To provide evidence-based recommendations for improving patient outcomes.

Main Methods:

  • Retrospective analysis of prospectively collected data from 183 patients undergoing purely laparoscopic MH (1998-2014).
  • Inclusion of demographic, clinicopathological, and perioperative factors.
  • Statistical analysis to determine independent risk factors for overall and major complications (Dindo-Clavien grade III or above).

Main Results:

  • Overall complications occurred in 54.6% of patients; major complications (grade III+) were also assessed.
  • Intraoperative simultaneous radiofrequency ablation (RFA) was an independent risk factor for global complications (OR 6.93).
  • Intraoperative blood transfusion (OR 2.50) and bilobar resection (OR 2.47) were independent risk factors for major complications.

Conclusions:

  • Purely laparoscopic major hepatectomy is a feasible and safe procedure.
  • Simultaneous RFA and bilobar resection are associated with increased risk and should be avoided.
  • Findings guide surgical decision-making to minimize complications in laparoscopic MH.