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Updated: Apr 19, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Two new pyrone derivatives from the plant endophytic fungus Exserohilum sp
Abstract:
Two new a-pyrones, Exserolide G-H (1-2), together with one known metabolite, stemphypyrone (3), were isolated from the solid-substrate fermentation cultures of the plant endophytic fungus Exserohilum sp. The structures of the new compounds were elucidated primarily by analysis of NMR data. Compounds 1-3 were tested for cytotoxicity against a small panel of human carcinoma cell lines. Compound 1 showed cytotoxicity against HeLa, A549 and HCT116 cells.
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