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Related Experiment Video

Updated: Apr 19, 2026

Studying Orthodontic Tooth Movement in Mice

Studying Orthodontic Tooth Movement in Mice

Published on: August 2, 2024

Are interventions for accelerating orthodontic tooth movement effective?

Mohamed-Nur Abdallah¹, Carlos Flores-Mir²

¹Faculty of Dentistry, McGill University, Quebec, Canada.

Evidence-Based Dentistry

|December 20, 2014

Summary

Corticotomy effectively accelerates orthodontic tooth movement. Low-level laser therapy does not accelerate tooth movement, while electrical current, pulsed electromagnetic fields, and distraction osteogenesis show promising but inconclusive results.

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Last Updated: Apr 19, 2026

Studying Orthodontic Tooth Movement in Mice

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Published on: August 2, 2024

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Author Spotlight: Insights into an Efficient Murine Maxillary Orthodontic Model Protocol

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Author Spotlight: 3D Movement Assessment of Maxillary Posterior Teeth in Clear Aligner Treatment

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Area of Science:

Orthodontics
Biomaterials Science
Regenerative Medicine

Background:

Accelerating orthodontic tooth movement is a significant clinical goal.
Various interventions are being explored to enhance the rate of tooth movement during orthodontic treatment.

Purpose of the Study:

To systematically review and synthesize evidence on interventions aimed at accelerating orthodontic tooth movement.

Main Methods:

Searched multiple databases (PubMed, Embase, etc.) for randomized controlled trials (RCTs) and quasi-RCTs published between 1990 and 2011.
Included studies on healthy participants receiving interventions alongside conventional orthodontic treatment.
Excluded participants with maxillofacial defects, dental pathologies, or specific medical conditions.

Main Results:

Included nine studies (7 RCTs, 2 quasi-RCTs) with 101 participants (aged 12-26.3 years).
Corticotomy (CS) showed significantly higher movement rate and accumulative moved distance. Low-level laser therapy (LLL) did not demonstrate acceleration.
Electrical current (EC) and pulsed electromagnetic fields (PEF) showed some positive effects on movement rate, while dentoalveolar distraction (DAD) and periodontal distraction (PDD) showed promise.

Conclusions:

Corticotomy is an effective and safe method for accelerating orthodontic tooth movement.
Low-level laser therapy is not effective for accelerating orthodontic tooth movement.
Evidence for electrical current, pulsed electromagnetic fields, and distraction techniques is promising but requires further investigation.