Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

856
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
856
Cancer Prevention02:59

Cancer Prevention

8.7K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
8.7K
Cancer Prevention02:59

Cancer Prevention

3.1K
3.1K
Longitudinal Research02:20

Longitudinal Research

13.7K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.7K
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

5.1K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
5.1K
Comparing the Survival Analysis of Two or More Groups01:20

Comparing the Survival Analysis of Two or More Groups

728
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
728

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perspectives on communication and engagement with regard to collecting biospecimens and family health histories for cancer research in a rural Alaska Native community.

Journal of community genetics·2019
Same author

A Framework for Culturally Relevant Online Learning: Lessons from Alaska's Tribal Health Workers.

Journal of cancer education : the official journal of the American Association for Cancer Education·2018
Same author

Occurrence of Endocrine and Thyroid Cancers Among Alaska Native People, 1969-2013.

Thyroid : official journal of the American Thyroid Association·2018
Same author

Culturally-Relevant Online Cancer Education Modules Empower Alaska's Community Health Aides/Practitioners to Disseminate Cancer Information and Reduce Cancer Risk.

Journal of cancer education : the official journal of the American Association for Cancer Education·2017
Same author

Cancer among circumpolar populations: an emerging public health concern.

International journal of circumpolar health·2016
Same author

Case-control study of breast cancer and exposure to synthetic environmental chemicals among Alaska Native women.

International journal of circumpolar health·2014

Related Experiment Video

Updated: Apr 19, 2026

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis
09:45

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis

Published on: March 31, 2015

11.9K

Cancer disparities among Alaska native people, 1970-2011.

Janet J Kelly1, Anne P Lanier2, Teresa Schade2

  • 1Alaska Native Tribal Health Consortium, Alaska Native Epidemiology Center, Division of Community Health Services, 3900 Ambassador Dr, Anchorage, Alaska 99508. Telephone: 907-729-3949.

Preventing Chronic Disease
|December 20, 2014
PubMed
Summary

Cancer incidence is higher in Alaska Native women than US white women. Colorectal cancer incidence is declining, but mortality rates remain high for Alaska Native people, indicating a need for improved cancer control strategies.

More Related Videos

Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies
07:47

Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies

Published on: September 15, 2023

2.4K
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

1.0K

Related Experiment Videos

Last Updated: Apr 19, 2026

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis
09:45

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis

Published on: March 31, 2015

11.9K
Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies
07:47

Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies

Published on: September 15, 2023

2.4K
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

1.0K

Area of Science:

  • Oncology
  • Epidemiology
  • Public Health

Background:

  • Cancer is the leading cause of death for Alaska Native people.
  • This study examines cancer incidence and mortality trends in Alaska Native populations.

Purpose of the Study:

  • To analyze cancer incidence data from 2007-2011.
  • To assess age-specific cancer rates over 15 years.
  • To evaluate cancer incidence and mortality trends from 1970-2011 and 1990-2011, respectively.

Main Methods:

  • Utilized data from the Surveillance, Epidemiology, and End Results (SEER) Program and the SEER Alaska Native Tumor Registry.
  • Compared age-adjusted cancer incidence rates between Alaska Native people and US whites.
  • Performed trend analyses using Joinpoint Regression Program and mortality data from the National Center for Health Statistics.

Main Results:

  • Alaska Native women had a 16% higher cancer incidence rate than US white women (2007-2011).
  • Incidence rates for nasopharyngeal, stomach, colorectal, lung, and kidney cancers were higher in Alaska Native people.
  • Colorectal cancer incidence showed a downward trend (1999-2011), but overall cancer mortality rates did not decline and exceeded those of US whites.

Conclusions:

  • Declines in colorectal cancer incidence may be linked to increased screening and improved treatment.
  • Persistent high cancer mortality rates highlight the need for enhanced cancer prevention and control efforts in Alaska Native populations.