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Conventional drug therapy for inflammatory bowel disease
Robert V Bryant1, Oliver Brain, Simon P L Travis
1Translational Gastroenterology Unit, Oxford University Hospitals Trust , Oxford , UK.
Scandinavian Journal of Gastroenterology
|December 20, 2014
Summary
This review provides a practical guide to conventional therapies for inflammatory bowel diseases (IBD), covering drug efficacy and safety. It focuses on established treatments like aminosalicylates and biologics for better patient management.
Area of Science:
- Gastroenterology and Hepatology
- Clinical Pharmacology
Background:
- Conventional medical therapy remains the primary treatment for most inflammatory bowel diseases (IBD) patients.
- Emerging IBD therapies are often restricted by healthcare regulations and availability at specialized centers.
Purpose of the Study:
- To offer a pragmatic approach to conventional IBD therapy based on current evidence.
- To guide optimal and appropriate clinical practice for managing IBD.
Main Methods:
- Systematic review of current evidence on conventional IBD therapies.
- Analysis of drug efficacy, safety profiles, and practice points.
Main Results:
- Conventional therapies discussed include aminosalicylates, corticosteroids, thiopurines, methotrexate, calcineurin inhibitors, infliximab, and adalimumab.
- Key considerations for efficacy, safety, and practical application are addressed for each agent.
Conclusions:
- This review synthesizes evidence to support practical decision-making in conventional IBD treatment.
- Optimal use of established therapies is crucial for effective and safe management of inflammatory bowel diseases.
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