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Coronary artery disease in thrombotic aneurysm of the abdominal aorta

F Massoni1, C Simeone1, P Ricci1

  • 1Department of Anatomical sciences, histological, legal medicine and locomotor apparatus. University "Sapienza" of Rome, Italy.

La Clinica Terapeutica
|December 20, 2014
PubMed

Insights

Abdominal Aortic Aneurysm (AAA) rupture is a common cause of death. However, this case report highlights that even large AAAs with IntraLuminal Thrombosis (ILT) may not be the direct cause of death, suggesting other factors can be fatal.

Area of Science:

  • Cardiovascular Science
  • Pathology
  • Vascular Surgery

Background:

  • Abdominal Aortic Aneurysm (AAA) rupture is a leading cause of mortality.
  • IntraLuminal Thrombosis (ILT) within AAAs is associated with increased rupture risk.
  • However, non-rupture related deaths in AAA patients occur.

Observation:

  • This report details an autopsy of a patient with a large AAA and significant ILT.
  • The patient's cause of death was determined to be heart failure secondary to Coronary Artery Disease (CAD).
  • This contrasts with the typical AAA rupture mortality.

Findings:

  • The presence of ILT did not directly lead to AAA rupture or death in this case.
  • The patient succumbed to complications of thrombotic and ischemic heart disease.
  • Potential protective roles of ILT or thrombotic products might influence AAA outcomes.

Implications:

  • AAA management strategies should consider non-rupture related comorbidities.
  • Further research into the complex role of ILT in AAA pathogenesis is warranted.
  • Autopsy findings provide critical insights into diverse AAA patient mortality factors.

Keywords:
Aneurysm of the abdominal aortaCoronary artery diseaseIschemic heart disease

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