Does non-pharmacological treatment affect outcomes in dysautonomic syndromes?

Dysautonomic syndromes are very common clinical conditions with different presentations and a wide spectrum of mechanisms. Many non-pharmacological and pharmacological interventions have been recommended to treat dysautonomic patients along these years, but the majority of them were not supported by multicenter controlled trials. General measures, like water drinking and salt intake, avoiding triggers and recognizing prodromal symptoms, as well as performing orthostatic training and physical conditioning are commonly able to improve symptoms and avoid syncope and falls. In this article, we will explore why and how such measures are applied to treat patients with dysautonomic syndromes, based on the physiopathology of these disorders.