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Published on: August 4, 2012
Feigning acute intermittent porphyria
Rania Elkhatib1, Modupe Idowu2, Gregory S Brown3
1Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 5656 Kelley Street, Houston, TX 77026, USA.
Abstract:
Acute intermittent porphyria (AIP) is an autosomal dominant genetic defect in heme synthesis. Patients with this illness can have episodic life-threatening attacks characterized by abdominal pain, neurological deficits, and psychiatric symptoms. Feigning this illness has not been reported in the English language literature to date. Here, we report on a patient who presented to the hospital with an acute attack of porphyria requesting opiates. Diligent assessment of extensive prior treatment records revealed thirteen negative tests for AIP.
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