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Radiogenomics: the search for genetic predictors of radiotherapy response

Sarah L Kerns1, Catharine M L West, C Nicolaj Andreassen

  • 1Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Future Oncology (London, England)
|December 20, 2014
PubMed
Summary

Radiogenomics, the study of genetic variation in radiotherapy response, aims to identify genetic markers for predicting patient outcomes and developing targeted radioprotective agents. This field is advancing toward clinical application through genome-wide association studies.

Keywords:
genome-wide association studynormal tissue toxicityradiogenomicsradiotherapysingle nucleotide polymorphisms

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