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Updated: Apr 19, 2026

Establishing a Competing Risk Regression Nomogram Model for Survival Data
Published on: October 23, 2020
BMI variation increases recurrence risk in women with early-stage breast cancer
Palma Fedele1, Laura Orlando, Paola Schiavone
1Medical Oncology & Breast Unit, 'A Perrino' Hospital, SS 7 Appia, 72100 Brindisi, Italy.
Aims:
The prognostic role of BMI variation during and/or after treatments for early-stage breast cancer is still unknown.
Patients & Methods:
The χ(2) test was conducted to explore the correlation between breast cancer recurrence and BMI changes in 520 early-stage breast cancer patients. Cox proportional hazard models were used to analyze the association of BMI changes, baseline BMI, known prognostic factors and recurrences.
Results:
BMI gain was significant determinant of recurrences (p = 0.0008). In multivariate analyses, BMI variation more than 5.71% was associated with higher rates of recurrences, as well as age less than 55 years, stage disease and molecular subtype.
Conclusion:
Women who experience BMI gain after breast cancer may be at increased risk of poor outcomes.
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