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Published on: July 24, 2020
Spectral Domain OCT Imaging Techniques in Tamoxifen Retinopathy
Jessica Neuville1, Vladimir Yevseyenkov
1*OD, FAAO †OD, PhD, FAAO Midwestern University, Arizona College of Optometry, Glendale, Arizona (both authors).
Purpose:
To highlight the use of high-density spectral domain optical coherence tomography (SD-OCT) in the detection of tamoxifen retinopathy.
Case Report:
An 82-year-old asymptomatic woman with a history of tamoxifen therapy for breast cancer was found to have bilateral refractile retinal deposits on fundus examination. Detection on SD-OCT was compared across imaging techniques. High-density SD-OCT demonstrated hyperreflective deposits in the inner retinal layers of each eye consistent with the diagnosis of tamoxifen retinopathy.
Conclusions:
The optimal SD-OCT scan technique depends on the ocular condition being imaged. High-density scan techniques require longer acquisition time but may enhance the detection of focal retinal pathology.

