Related Experiment Video
Updated: Apr 19, 2026

An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
Acute myocardial infarction with no obstructive coronary atherosclerosis: mechanisms and management
Giampaolo Niccoli1, Giancarla Scalone2, Filippo Crea3
1Institute of Cardiology, Catholic University of the Sacred Heart, Largo Agostino Gemelli, 8, Rome 00168, Italy gniccoli73@hotmail.it.
Abstract:
Myocardial infarction (MI) with no obstructive coronary atherosclerosis (MINOCA) is a syndrome with different causes. Its prevalence ranges between 5 and 25% of all MIs. The prognosis is extremely variable, depending on the causes of MINOCA. Clinical history, echocardiography, coronary angiography, and left ventriculography represent the first-level diagnostic investigations. Nevertheless, additional tests are required in order to establish its specific cause, thus allowing an appropriate risk stratification and treatment. We review pathogenesis, diagnosis, prognosis, and therapy of MINOCA and propose an algorithm for its management.
Related Concept Videos
Atherosclerosis III: Management
Angina IV: Management
Acute Coronary Syndrome IV: Interprofessional Care
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis IV: Nursing Management
Coronary Artery Disease V: Interprofessional Care
