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Related Concept Videos

Deformation of Member under Multiple Loadings01:11

Deformation of Member under Multiple Loadings

640
When a rod is made of different materials or has various cross-sections, it must be divided into parts that meet the necessary conditions for determining the deformation. These parts are each characterized by their internal force, cross-sectional area, length, and modulus of elasticity. These parameters are then used to compute the deformation of the entire rod.
In the case of a member with a variable cross-section, the strain is not constant but depends on the position. The deformation of an...
640

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Related Experiment Video

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How much will linked deformable registrations decrease the quality of multi-atlas segmentation fusions?

Carl Sjöberg1,2, Silvia Johansson3, Anders Ahnesjö4

  • 1Section for Medical Radiation Physics, Department of Radiology, Oncology and Radiation Sciences, Uppsala University, Akademiska Sjukhuset, Sjukhusfysik Ing. 82, SE-751 85, Uppsala, Sweden. carl.sjoberg@onkologi.uu.se.

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Summary
This summary is machine-generated.

Linking pre-calculated registrations significantly reduces computation time for multi-atlas segmentation. This method offers a feasible approach to accelerate medical image analysis while maintaining acceptable segmentation quality for clinical applications.

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Area of Science:

  • Medical imaging analysis
  • Computational anatomy
  • Radiation oncology

Background:

  • Multi-atlas segmentation improves accuracy over single-atlas methods.
  • Deformable registration in multi-atlas segmentation is computationally intensive.
  • Linking pre-calculated registrations offers a potential solution to reduce computation time.

Purpose of the Study:

  • To investigate and quantify segmentation quality changes from linked registrations.
  • To determine optimal parameters for fusing linked multi-atlas labels.
  • To evaluate the feasibility of linked registrations for reducing computation time.

Main Methods:

  • Computed tomography images of 10 head and neck cancer patients were used.
  • Segmentation of organs and lymph nodes by an experienced radiation oncologist.
  • Leave-one-out approach to assess Dice similarity coefficient (DSC) changes with B-spline free-form deformable registrations.

Main Results:

  • Median DSC decrease ranged from 2.8% to 8.4% compared to direct registrations.
  • Computation time was reduced to that of a single deformable registration.
  • DSC decrease was nearly linear with the number of links, enabling observer-independent precision assessment.

Conclusions:

  • Linking pre-made registrations via a single runtime-registered atlas is feasible.
  • This method effectively reduces computation time in multi-atlas registration.
  • The approach maintains acceptable segmentation quality for practical applications.