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Updated: Apr 19, 2026

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings
Published on: August 1, 2018
Aging alters visual processing of objects and shapes in inferotemporal cortex in monkeys
G Csete1, A Bognár2, P Csibri2
1Department of Physiology, Faculty of Medicine, University of Szeged, Dóm tér 10, H-6720 Szeged, Hungary; Department of Neurology, Faculty of Medicine, Semmelweis u. 6, H-6725 Szeged, Hungary.
Abstract:
Visual perception declines with age. Perceptual deficits may originate not only in the optical system serving vision but also in the neural machinery processing visual information. Since homologies between monkey and human vision permit extrapolation from monkeys to humans, data from young, middle aged and old monkeys were analyzed to show age-related changes in the neuronal activity in the inferotemporal cortex, which is critical for object and shape vision. We found an increased neuronal response latency, and a decrease in the stimulus selectivity in the older animals and suggest that these changes may underlie the perceptual uncertainties found frequently in the elderly.
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