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Updated: Apr 19, 2026

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
Published on: November 9, 2019
Synthesis of a new class of Betti bases by the Mannich-type reaction: efficient, facile, solvent-free and one-pot
Aziz Shahrisa1, Reza Teimuri-Mofrad, Mahdi Gholamhosseini-Nazari
1Department of Organic and Biochemistry, Faculty of Chemistry, University of Tabriz, 5166614766, Tabriz, Iran, ashahrisa@yahoo.com.
Abstract:
A variety of organocatalysts has been screened for the synthesis of arylaminonaphthols. It has been shown that (N,N-dimethylethanolamine) is a highly efficient organocatalyst for the direct synthesis of a novel class of arylaminonaphthols via three-component condensation of 2-naphthol, aldehydes, and arylamines under solvent-free conditions. Mild, one-pot, and green reaction conditions, relatively short reaction times and good yields make this protocol highly significant. 25 new compounds have been synthesized by this method.
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