Related Experiment Video
Updated: Apr 19, 2026
Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
Published on: February 6, 2019
The premotor role of the prefrontal cortex in response consistency
Rinaldo Livio Perri1, Marika Berchicci1, Giuliana Lucci1
1Department of Human Movement, Social and Health Sciences, University of Rome "Foro Italico"
Objective:
The aim of the present study was to investigate the cortical correlates of the intraindividual coefficient of variation (ICV) in a go/no-go task, focusing on the prefrontal cortex (PFC) contribution and evaluating both pre- and poststimulus brain activity.
Method:
We recorded event-related potentials (ERPs) in 40 subjects, arranged a posteriori in 2 groups on the basis of their ICV values. By this method, we formed the consistent (low ICV; n = 20) and inconsistent (high ICV; n = 20) group: the age, speed, and accuracy performance of the 2 groups were matched.
Results:
The prestimulus anticipatory PFC activity, as reflected by the prefrontal negativity (pN) wave, and the poststimulus P3 component were larger in the consistent than in the inconsistent group. In contrast, no differences were observed between groups in the brain activities associated to motor preparation and early sensory processing.
Conclusions:
Data are interpreted as an enhanced top-down control in consistent performers, likely characterized by a greater sustained attention on the task.
More Related Videos
13:20Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance
Published on: December 5, 2025
10:33Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis
Published on: June 20, 2012
Related Concept Videos
01:14Role of Cerebellum and Prefrontal Cortex in Memory
01:25Self-Regulation