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Updated: Jan 25, 2026

An Efficient Method for Adenovirus Production
Published on: June 10, 2021
[Gastroenteritis caused by enteric adenovirus serotypes 40 and 41. Preliminary study]
J Reina Prieto1, J Figuerola Mulet, C N Pericas Puigserver
1Servicio de Microbiología, Hospital Son Dureta, Palma de Mallorca.
Insights
This study found enteric adenoviruses (AE-40 and AE-41) in 1.8% of childhood gastroenteritis cases. These viral infections were self-limiting, with symptoms managed through diet and rehydration.
Area of Science:
- Pediatric Infectious Diseases
- Virology
- Gastroenterology
Context:
- Childhood gastroenteritis is a common ailment in pediatric populations.
- Enteric adenoviruses are increasingly recognized as a cause of pediatric enteritis.
Purpose:
- To investigate the prevalence and clinical characteristics of enteric adenovirus infections in children with gastroenteritis.
Summary:
- A prospective study identified enteric adenoviruses (types AE-40 and AE-41) in 9 out of 499 (1.8%) children presenting with enteritis.
- The affected children, with a mean age of 16.2 months, experienced diarrhea lasting an average of 2.8 days.
- Associated symptoms included respiratory issues in 44.4% of cases, and one co-infection with Campylobacter jejuni was noted.
Impact:
- This research highlights the role of specific enteric adenovirus types in pediatric gastroenteritis.
- Findings support the self-limiting nature of these infections and underscore the importance of supportive care like diet and rehydration.
Abstract:
We present the preliminary results of a prospective study of childhood gastroenteritis associated with enteric adenovirus (AE-40 and AE-41). In a period of five months we have studied 499 children with enteritis; 9 (1.8%) were positive for enteric adenoviruses (latex agglutination). The mean age of the children was 16.2 months (extreme ages 10 days and 5 years). The mean duration of diarrhoea was 2.8 days with 4-5 times daily. Respiratory symptoms were present in 44.4% of the patients and one patient was infected simultaneously with Campylobacter jejuni. All clinical syndromes were self-limiting and were treated with diet and rehydration.
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